Learn everything about Sodium methoxide

Sodium methoxide is a solid chemical compound that is either white or colourless in appearance. It is use in industries as a reagent. It create by removing hydrogen (H+) proton from Methanol.

The name Sodium methylates likewise recognizes this substance.

Sodium methoxide Physical Properties

It is a colourless chemical substance. It is mainly locate as a powder in the solid type. This substance has no smell. It has hygroscopic residential or commercial properties. The specific gravity of this substance at a temperature of 20 ° C is 1.1. The Refractive index for this chemical material is 1.3700.

Prep work of Sodium methoxide

Sodium methoxide develop by treating methyl alcohol with sodium. It is stood for the following reaction.

2Na + 2 CH3OH → 2 CH3ONa + H2

The solid crystals of this chemical substance are polymeric. They all have Na+ facilities arranged in sheet-like ranges, and each is combine with four oxygen centres.

It is essential to consider the nature of the solvent utilize while identifying the structure and pKa worth or the basicity of this chemical compound. In DMSO, Sodium methoxide has a fuller ionization reaction and is likewise devoid of any hydrogen bonding. It has hence a more powerful pKa value or basicity in DMSO.

Sodium methoxide from Sodium hydroxide

It can stem from Sodium hydroxide (NaOH) by responding to NaOH with Methylene. This reaction happens in the following means:

2 NaOH + 2 CH2 → 2 CH3ONa

Sodium methoxide Reactivity

The compound is usually steady under typical pressure conditions and average temperatures. Nevertheless, it can respond violently when found in contact with water, air, dampness or steam and may blow up or stir up. It creates Sodium Hydroxide and also Methanol in reaction with water. Methanol or Methyl Alcohol is a flammable fluid. Therefore, ensuring that the container saving CH3ONa is constantly kept dry is essential. The product is likewise highly combustible when available in contact with acids and chlorinated solvents.

This reaction is highly exothermic; naturally, ignition is possible. The service of Sodium methoxide is anaemic in hydrogen. This remedy is a source of Sodium methoxide, yet the chemical can likewise be drawn out from this remedy by evaporation through the application of warmth. This eliminates the recurring methyl alcohol and leaves the Sodium methoxide in the container.

The solid crystals of CH3ONa respond with water to create a hydrolytic reaction. Readily gotten examples are highly polluted with hydroxide impurities.


Sodium methoxide itself is not flammable. Nevertheless, it can break down drunk of heat and create hazardous and harsh fumes. It can also be an oxidizing agent and spark combustibles like wood, oil, paper or clothes. Containers keeping CH3ONa might take off drunk of heat.

Sodium methoxide in Methanol

This compound is a hazardously caustic solid base. It can cause shedding feelings in the skin as well as the eyes. Inhaling the dust may cause severe wellness damage. It is additionally ignitable and also responds violently to water. The substance also results in terrible explosions on reacting with alcohol, acids, oxidizing agents, and various other solvents. It is therefore strongly suggested that a remedy containing 25% Sodium methoxide is used while preparing the material in methanol reagent, offered such an opportunity is readily available.

Sodium methoxide Uses

Provided listed below are some uses for this compound:

Makes Use Of in Organic Chemistry

Sodium methoxide is taken into consideration to a strong base. It is thus regularly used in natural chemistry to synthesize numerous chemical substances such as drugs and agrichemicals. Likewise, it is use as a base in aldol condensations and dehydrohalogenations. It works as a nucleophile in the production of methyl ethers.

Uses in Drug Industry

In the pharmaceutical industry, the power of this substance is used in the manufacture of important like

Vitamin A1

Vitamin B1

Trimethoprim (TMP).




Utilizes in Biodiesel Industry.

In the Biodiesel Sector, it serves as an essential feature as a catalyst. Biodiesel is produced from fat triglycerides. These fatty acid triglycerides are mainly stemmed from pet fats and vegetable oils. Transesterification of fat triglycerides with Methanol generates fatty acid methyl esters or Popularities. Sodium methoxide is utilized in this chain reaction as a driver.

Various Other Uses of Sodium methoxide.

Some other uses of CH3ONa are as follows:

  • It is used as an edible stimulant along with an analytical reagent.
  • CH3ONa is made used to launch anionic enhancement polymerization of ethylene oxide. This generates a polyether having a high molecular weight.
  • It can likewise use for processing edible oils and fats and in the prep work of various other chemicals.
  • A small amount of this substance is utilized in the manufacturing of chemicals.
  • The material is used in the Wittig response even though it is a weak base than Butyllithium. This is since the pKa of alpha hydrogen in a Phosphine oxide compound is sufficiently reduced. This permits the combination to deprotonate them.
  • Sodium methoxide MSDS.
  • The Product Security Data Sheet (MSDS) for this material is as complies with.

Health and wellness Hazards.

The material can trigger significant damage to human and also animal health. It is a harmful chemical which can trigger damage to both interiors in addition to external organs.

Risks from Eye Direct Exposure: When the eyes come in contact with this compound, it can generate discomforting symptoms.

Burning sensation in eyes.

Irritability in eyes.





Hazards from Skin Direct exposure— The substance generates dangerous results in skin getting in touch. Severe burning and inflammation of the skin occur in such cases. Long-term direct exposure of the skin to this product may also create Dermatitis.

Interior Problems: The compound is highly poisonous and might create injury.


Mucous Membranes.

Reproductive System.

Nerve system.

Repetitive exposure to it can cause long-term damage to the body’s organs.

Risks from Inhalation: If breathed in, it can trigger extreme burning of the respiratory system. Damage to interior breathing body organs from unintended inhalation of chemical dirt is likewise an opportunity. Possible effects of inhalation consist of.

Sore throat and also nose.


Struggled breathing.

Lung oedema.


Chemical Pneumonitis.





Hazards from Intake: Upon unintended ingestion, it can create severe discomfort and also ultimately damage the digestive tract. Consumption can lead to the burning of the intestinal system. Other effects of accidental swallowing of the substance consist of

Aching throat

Looseness of the bowels

Throwing up

Abdominal Convulsions

Ingesting CH3ONa may also cause damage to the mouth, the oesophagus, and the throat.

Emergency Treatment Steps

Must use the following emergency treatment actions to manage conditions arising from exposure to this compound.

Eye direct exposure: In direct eye exposure, one must remove any contact lenses put on quickly. After that, the eyes ought to be purged with running water while keeping the eyelids open. This should be provided for a minimum of 15 to half an hour. You can splash the eyes with cold water. It is better not to use any eye lotion in these cases. Must consult a physician for additional clinical focus.

Skin direct exposure: Skin contact with this material leads to shedding feelings in the afflicted location. The contaminated skin location should be cleaned with great deals of running water and mild soap. We can use cold water for this function. Special attention needs to be provided while cleaning up particular locations, such as

Folds up




A cream ought to be put on the aggravated skin. A doctor should be gotten in touch with if the skin problems continue. Should clean the contaminated clothing and footwear thoroughly before reusing. If required, dirty clothes and shoes need to be damaged.

In case of significant skin infections, the contaminated areas should be washed with a disinfectant soap and put an anti-bacterial cream on the infected skin areas. A skin doctor ought to be sought advice for even more clinical help.

Unintentional inhalation: 

The targets of forced breathing must be taken to a well-aerated area where they can breathe freely. Must take treatment that the place is free of any chemical deposit. Must loosen tight garments such as connection, collar, waistband or belt. If breathing is still tricky, and oxygen supply is to be provided. Might also use artificial respiration using a mechanical device like a mask or a bag. Mouth-to-mouth resuscitation is not to be performed under any scenario. Moreover, should consult a physician to aid in these instances.

Accidental intake: 

While handling patients that have unintentionally consumed the material, care should be taken so as not to motivate throwing up. Can offer the victim two to 4 cups of water or milk if the sufferer is alert and mindful. Limited clothing loosens any type of should if the sufferer finds breathing difficult. Immediate medical interest is required in such instances to additional assist the victim.

Fire Threats

CH3ONa itself is not combustible. However, it can respond vigorously to water or foam to create flammable methyl alcohol. Under the visibility of a warm source, containers storing the product may likewise explode.

It emits poisonous as well as corrosive fumes on ignition. Vapours produced by the substance can take a trip to remote locations at a distance where they can get stirred up. After that, the fired-up mists can blink back to their factor of origin.

It can behave as an oxidizing agent and ignite compounds like paper, oil, wood or clothes.

The compound can also blow up when it reacts with air or dampness. Neighbouring triggers or flames can be harmful as they can cause fire breakouts. At times, it might re-ignite even after the fire is snuffed out.

Carbon compounds such as carbon monoxide gas and co2 are created from the combustion of Sodium methoxide.

Fire Battling Guidelines

Fire Combating Substances: Dry chemical powder should be used to prevent tiny fires. Various other compounds that can make use for snuffing out little fires are lime, soda ash and sand. Big fires can be snuffed out by

Dry chemical

Dry sand


Soda ash

Carbon dioxide

Fire Battling Preventative Measures: Not letting water enter the containers is essential. In large fires, professional firefighters need to be in touch immediately. The warm containers must cool down by splashing great deals of water over as well as around them also after the fires are snuffed out. This is necessary as the containers are require to cool down to stay clear of more fire outbreaks.

Defence Equipment Required for Fire Fighting– Unique precautions must observe while dealing with fire mishaps from this chemical. Special protection gear for firefighting should consist of MSHA/NIOSH (approved or equal) self-supporting breathing devices with pressure-demand oxygen masks. Other crucial security gears are

Security goggles with a face shield to secure from chemical dashes

Chemical immune clothing made from nitrile or neoprene

Chemical-resistant gloves constructed from nitrile or neoprene

Accidental Launch Steps

If CH3ONa is spilt mistakenly, the spills need to tidy up promptly following preventive actions reviewe below.

  • The leak should entirely supplied. There are no risks in doing so.
  • Should not touch the splash chemical with bare hands.
  • Should remove all fire resources from the area and must use spark-proof tools to manage the spills. Sufficient ventilation needed and also should treat to preserve the location dust-free.

The material must not be removed via sewage systems and cellars. A problem of an inert ambience ought to be kept in the location.

Under any circumstances, must not spill water on the chemical substances; the containers should also be maintained free of moisture.

Should cover the whole thing with a plastic sheet. A dry planet and arid sand can aid in soaking up the chemical. Water spray must minimize the vapours or divert the wandering of the vapour clouds.

You can minimize or stop the dispersing of this material by utilizing substances such as

Dry sand

Dry earth


Universal binders

Acid binders


Other non-combustible materials

Toxic wastes from Sodium methoxide

This is a toxic material and also can generate contaminated materials. Therefore it must not dispose of in the environment without appropriate governmental permission.

Required Concentration Level of the Chemical

 Should keep the concentration degree below the Threshold Limit Value or TLV. For Sodium methoxide, the TLV dimension is 220ppm to skin.

Handling of Sodium methoxide

While dealing with Sodium methoxide, the following factors should kept in mind.

  • It ought to kept in an inert environment.
  • The storage location must well ventilated and also dust-free.
  • The material should not inhale, consumed, or touched straight with bare hands. Successive contact with clothes should also stay clear.
  • Avoid water, wetness or heavy steam in addition to any source of warmth, flame or triggers. Must also safeguard it versus solid electrostatic costs.
  • The containers should snugly closed so as avoid contact with air.
  • The substance ought to not pressurize. Activities such as cutting, brazing, welding, soldering, grinding and drilling near the chemical need to clear as these may bring about sparks.
  • Sodium methoxide should kept from compounds such as alcohols, acids, halogens, esters, and ketones.

Storage space for Sodium methoxide

The material needs to store adhering to particular preventive steps. Sodium methoxide must kept in tight shut, dry containers under argon or nitrogen. should keep it far from substances such as

Water or wetness

Oxidizing agents


Heat, fires or sparks

Strong Acids



It must preferably save the containers in a cooled space. Accessibility to this area needs to restrict. Only technical specialists and their assistants must have accessibility to this space.

Transport of Sodium methoxide

Some vital info connecting to the transport of this compound is discus below:

Sodium methoxide has identifies as Risk Course 4.2.

The UN Number for this chemical is 1431.

It comes from the Packing group II of medium threat.

The Kemler threat code for this material is 48.

The International Maritime Dangerous Goods Code for maritime transportation of this chemical is 4.2.

In the case of air transport, this material has been classified as ICAO/IATA course 4.2.

Sodium methoxide Cost

CH3ONa is available in major chemical stores. Numerous brand names produce and also stock CH3ONa. You can additionally purchase Sodium methoxide from online shops. Sodium methoxide can brought as solid crystals.